Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366329 | 0.90 | KDM4E (0.50) | KDM4E | |
| SCHEMBL10280356 | 0.85 | KDM4E (0.61) | PPARGGAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL366931 | 0.84 | CNR1 (0.42) | CNR1GAAKDM4EALDH1A1 | |
| SCHEMBL365016 | 0.82 | KDM4E (0.50) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL365439 | 0.81 | KDM4E (0.48) | GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL366286 | 0.80 | MAPT (0.48) | GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL364682 | 0.80 | KMT2A (0.58) | GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL365132 | 0.80 | ALDH1A1 (0.46) | GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL366943 | 0.79 | KDM4E (0.46) | GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL365760 | 0.78 | KDM4E (0.53) | GAASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |