Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 4/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188363 | 0.80 | ALDH1A1 (0.40) | CYP19A1RIPK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13096520 | 0.80 | CHRNB2 (0.54) | CFBCYP19A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL22473220 | 0.80 | TRPA1 (0.44) | — | |
| SCHEMBL22473531 | 0.80 | TRPA1 (0.44) | — | |
| SCHEMBL26818027 | 0.80 | PSEN1 (0.43) | RIPK1CHRNA7 | |
| SCHEMBL13676331 | 0.79 | CHRNB2 (0.53) | CFBRIPK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15831466 | 0.79 | CHRNB2 (0.53) | CFBRIPK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15831467 | 0.79 | CHRNB2 (0.53) | CFBRIPK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL26818028 | 0.78 | PSEN1 (0.43) | RIPK1CHRNA7 | |
| SCHEMBL24775157 | 0.78 | CHRNB2 (0.51) | CFBRIPK1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240028-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009073210-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC (US) | 2009-06-11 | — | — | WO | disclosed |