Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663497 | 0.90 | NPC1 (0.53) | ADORA3MAPTALDH1A1HPGDTRPV1 | |
| SCHEMBL6524914 | 0.85 | KMT2A (0.50) | ADORA3MAPTALDH1A1HPGDTRPV1 | |
| SCHEMBL12791164 | 0.85 | HTT (0.55) | ADORA3MAPTALDH1A1HPGDTRPV1 | |
| SCHEMBL12791098 | 0.85 | ALDH1A1 (0.52) | ADORA3MAPTALDH1A1HPGDTRPV1 | |
| SCHEMBL6517154 | 0.79 | L3MBTL1 (0.57) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL3668412 | 0.79 | ALDH1A1 (0.55) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL12791258 | 0.73 | SMN1; SMN2 (0.48) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL12791142 | 0.73 | SMN1; SMN2 (0.48) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL3665405 | 0.72 | SMN1; SMN2 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL3663483 | 0.72 | SMN1; SMN2 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240461-A1 | SUBSTITUTED FURANS AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009097991-A1 | SUBSTITUTED FURANS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-13 | — | — | WO | disclosed |