Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663494 | 0.90 | ADORA3 (0.50) | NPC1RAB9AADORA3MAPTALDH1A1 | |
| SCHEMBL6524914 | 0.85 | KMT2A (0.50) | NPC1RAB9AADORA3MAPTALDH1A1 | |
| SCHEMBL12791164 | 0.85 | HTT (0.55) | NPC1ADORA3MAPTALDH1A1HPGD | |
| SCHEMBL12791098 | 0.85 | ALDH1A1 (0.52) | NPC1ADORA3MAPTALDH1A1HPGD | |
| SCHEMBL6517154 | 0.79 | L3MBTL1 (0.57) | NPC1MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL3668412 | 0.79 | ALDH1A1 (0.55) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL12791142 | 0.73 | SMN1; SMN2 (0.48) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL12791258 | 0.73 | SMN1; SMN2 (0.48) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL3665405 | 0.72 | SMN1; SMN2 (0.47) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL3663483 | 0.72 | SMN1; SMN2 (0.47) | NPC1RAB9AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240461-A1 | SUBSTITUTED FURANS AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009097991-A1 | SUBSTITUTED FURANS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-13 | — | — | WO | disclosed |