Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366150 | 0.84 | KMT2A (0.48) | S1PR3KDM4EHTTSMN1; SMN2MAPK1 | |
| SCHEMBL364302 | 0.83 | KMT2A (0.48) | KDM4EHTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL366362 | 0.83 | SMN1; SMN2 (0.54) | KDM4EHTTSMN1; SMN2MAPK1EGFR | |
| SCHEMBL365013 | 0.82 | KDM4E (0.58) | KDM4EHTTMAPK1EGFRSRC | |
| SCHEMBL365703 | 0.81 | KMT2A (0.50) | KDM4EKMT2AMAPTTP53 | |
| SCHEMBL365564 | 0.81 | KMT2A (0.56) | KDM4EHTTSMN1; SMN2MAPK1EGFR | |
| SCHEMBL364593 | 0.78 | KMT2A (0.56) | KDM4EHTTSMN1; SMN2MAPK1EGFR | |
| SCHEMBL364968 | 0.77 | KDM4E (0.70) | KDM4EHTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL365407 | 0.76 | ALDH1A1 (0.58) | S1PR3KDM4ESMN1; SMN2MAPK1MEN1 | |
| SCHEMBL364206 | 0.76 | KMT2A (0.54) | KDM4EHTTSMN1; SMN2MAPK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |