Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022635 | 0.76 | MTNR1A (0.36) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3008126 | 0.75 | MTNR1A (0.34) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3020288 | 0.72 | RIPK1 (0.36) | MTNR1AMTNR1BRIPK1MAPK1CRBN | |
| SCHEMBL3020759 | 0.71 | MTNR1A (0.38) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3030115 | 0.69 | KCNH2 (0.38) | RIPK1MEN1KMT2ACRBN | |
| SCHEMBL3663718 | 0.69 | MTNR1A (0.34) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3009533 | 0.68 | MTNR1A (0.36) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3016078 | 0.67 | MTNR1A (0.35) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3016071 | 0.67 | MTNR1A (0.35) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL20722710 | 0.66 | MTNR1A (0.35) | MTNR1AMTNR1BCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |