Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.58 |
| ▸ | MEP1B | Q16820 | 4/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421808 | 0.93 | FOLH1 (0.66) | FOLH1MEP1BMRGPRX4ANPEPENPEP | |
| SCHEMBL27705268 | 0.86 | FOLH1 (0.58) | FOLH1MEP1BMRGPRX4ANPEPENPEP | |
| SCHEMBL27705284 | 0.81 | FOLH1 (0.56) | FOLH1MEP1BMRGPRX4ANPEPENPEP | |
| SCHEMBL27752467 | 0.81 | FOLH1 (0.58) | FOLH1MEP1BANPEPENPEP | |
| SCHEMBL765921 | 0.80 | FOLH1 (0.61) | FOLH1MEP1BMRGPRX4ANPEPENPEP | |
| SCHEMBL12806220 | 0.79 | MAOB (0.51) | FOLH1MRGPRX4RAB9A | |
| SCHEMBL1777321 | 0.79 | FOLH1 (0.68) | FOLH1MEP1BMRGPRX4ANPEPENPEP | |
| SCHEMBL14478232 | 0.79 | ANPEP (0.69) | FOLH1ANPEPENPEP | |
| SCHEMBL8375490 | 0.79 | FOLH1 (0.59) | FOLH1MEP1BMRGPRX4ANPEPENPEP | |
| SCHEMBL9622159 | 0.79 | ANPEP (0.69) | FOLH1ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155711-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | Sanofi-Aventis (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008151211-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | SANOFI-AVENTIS (FR) | 2008-12-11 | — | — | WO | disclosed |