SCHEMBL3663904

SCHEMBL3663904

Cc1ccc(S(=O)(=O)n2c3ccccc3c3cc(-n4c5ccccc5c5cc(-n6c7ccccc7c7ccccc76)ccc54)ccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.52
PSEN1 P49768 2/20 0.52
PSEN2 P49810 2/20 0.52
APH1B Q8WW43 2/20 0.52
NCSTN Q92542 2/20 0.52
APH1A Q96BI3 2/20 0.52
PSENEN Q9NZ42 2/20 0.52
AGTR1 P30556 3/20 0.49
GAA P10253 2/20 0.47
ALDH3A1 P30838 2/20 0.47
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PCSK9 Q8NBP7 2/20 0.46
NOD1 Q9Y239 2/20 0.45
CXCL8 P10145 1/20 0.45
NOD2 Q9HC29 1/20 0.45
KDM4E B2RXH2 1/20 0.45
UBE2N P61088 1/20 0.45
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16685446 1.00 HTR6 (0.52) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL1278376 1.00 HTR6 (0.52) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL29355943 1.00 HTR6 (0.52) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL16397416 0.92 PSEN1 (0.58) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL15910203 0.92 AGTR1 (0.51) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL25540537 0.92 AGTR1 (0.51) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL17287199 0.92 PSEN1 (0.46) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL16398112 0.91 PSEN1 (0.57) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL17102412 0.90 PSEN1 (0.44) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL17165566 0.90 PSEN1 (0.44) HTR6PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240446-B2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-09-19 EP disclosed
EP-2240446-B1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2015-11-11 EP disclosed
WO-2014115743-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT USING SAME 国立大学法人九州大学 (JP) 2014-07-31 WO disclosed
US-8221905-B2 Carbazole-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-07-17 US disclosed
EP-2240446-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-10-20 EP disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 HTR6 3769/4885PSEN1 2622/4885PSEN2 2918/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L HTR6 4367/4885PSEN1 2600/4885PSEN2 2946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.