SCHEMBL17102412

SCHEMBL17102412

Cc1ccc(S(=O)(=O)n2c3ccccc3c3cc(-n4c5ccccc5c5cc(C#N)ccc54)ccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 2/20 0.44
PSEN2 P49810 2/20 0.44
APH1B Q8WW43 2/20 0.44
NCSTN Q92542 2/20 0.44
APH1A Q96BI3 2/20 0.44
PSENEN Q9NZ42 2/20 0.44
HTR6 P50406 6/20 0.44
AGTR1 P30556 3/20 0.42
GAA P10253 2/20 0.39
ALDH3A1 P30838 2/20 0.39
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PCSK9 Q8NBP7 2/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
NOD1 Q9Y239 2/20 0.38
CXCL8 P10145 1/20 0.38
NOD2 Q9HC29 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16685446 0.90 HTR6 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1278376 0.90 HTR6 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL3663904 0.90 HTR6 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29355943 0.90 HTR6 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16397416 0.82 PSEN1 (0.58) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL25540537 0.82 AGTR1 (0.51) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL17287199 0.82 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15910203 0.82 AGTR1 (0.51) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16398112 0.81 PSEN1 (0.57) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL17165566 0.80 PSEN1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12414463-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG SDI CO., LTD. (KR) 2025-09-09 US disclosed
US-20200203625-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2020-06-25 US disclosed
EP-3061759-B1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO (JP) 2019-12-25 EP disclosed
EP-3061759-B1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO (JP) 2019-12-25 EP disclosed
EP-3119770-B1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES IDEMITSU KOSAN CO (JP) 2018-05-02 EP disclosed
EP-3119770-B1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES IDEMITSU KOSAN CO (JP) 2018-05-02 EP disclosed
US-20170098781-A1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES IDEMITSU KOSAN CO., LTD. (JP) 2017-04-06 US disclosed
US-20170098781-A1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES IDEMITSU KOSAN CO., LTD. (JP) 2017-04-06 US disclosed
US-20170098781-A1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES IDEMITSU KOSAN CO., LTD. (JP) 2017-04-06 US disclosed
EP-3119770-A1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES Idemitsu Kosan Co., Ltd (JP) 2017-01-25 EP disclosed
EP-3061759-A1 NITRILE SUBSTITUTED DIBENZOFURANS Idemitsu Kosan Co., Ltd (JP) 2016-08-31 EP disclosed
EP-3061759-A1 NITRILE SUBSTITUTED DIBENZOFURANS Idemitsu Kosan Co., Ltd (JP) 2016-08-31 EP disclosed
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO., LTD. (JP) 2016-08-25 US disclosed
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO., LTD. (JP) 2016-08-25 US disclosed
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO., LTD. (JP) 2016-08-25 US disclosed
WO-2015140073-A1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES IDEMITSU KOSAN CO., LTD. (JP) 2015-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12414463-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 PSEN1 1306/4885PSEN2 1108/4885APH1B 379/4885
US-20170098781-A1 NEW DIBENZOFURANS AND DIBENZOTHIOPHENES DBF4, DDT, SLC43A3 PSEN1 2145/4885PSEN2 2887/4885APH1B 2758/4885
US-20200203625-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 PSEN1 1306/4885PSEN2 1108/4885APH1B 379/4885
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS DBF4, NXF1, NCF1 PSEN1 1553/4885PSEN2 2101/4885APH1B 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.