SCHEMBL634151

SCHEMBL634151

CNC(=O)c1cc(Br)cc(C)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
CREBBP Q92793 1/20 0.40
PKM P14618 1/20 0.38
MAPT P10636 6/20 0.38
HTT P42858 3/20 0.35
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.35
CFTR P13569 1/20 0.35
IKBKB O14920 1/20 0.35
GAA P10253 1/20 0.34
GLA P06280 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MMP1 P03956 1/20 0.34
MMP9 P14780 1/20 0.34
MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31400010 0.92 CREBBP (0.38) KDM4ECREBBPPKMMAPTHTT
SCHEMBL27953419 0.84 CREBBP (0.41) KDM4ECREBBPMAPTHTTALDH1A1
SCHEMBL3206636 0.81 ALOX5 (0.46) KDM4EPKMMAPTHTTALDH1A1
SCHEMBL29101565 0.81 KDM4E (0.39) KDM4EPKMMAPTALDH1A1SMN1; SMN2
SCHEMBL2061038 0.81 HDAC1 (0.44) CREBBPMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL30784326 0.81 CREBBP (0.39) KDM4ECREBBPPKMMAPTHTT
SCHEMBL29750651 0.80 KDR (0.49) KDM4ECREBBPPKMMAPTHTT
SCHEMBL21262077 0.80 KDR (0.49) KDM4ECREBBPPKMMAPTHTT
SCHEMBL2154955 0.79 KDM4E (0.46) KDM4EPKMMAPTHTTALDH1A1
SCHEMBL221718 0.79 KDM4E (0.66) KDM4EMAPTGLAPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619842-A Preparation method of 2-amino-5-bromo-N, 3-dimethylbenzamide 浙江予睿化学科技有限公司 2024-09-10 CN claimed
US-20250368602-A1 PROCESS FOR PREPARING CYANO SUBSTITUTED ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2025-12-04 US disclosed
WO-2025134143-A1 A METHOD FOR THE SYNTHESIS OF SUBSTITUTED ANTHRANILIC AMIDE COMPOUNDS, INTERMEDIATES AND SALTS THEREOF PI INDUSTRIES LTD. (IN) 2025-06-26 WO disclosed
WO-2025134140-A1 A METHOD FOR THE SYNTHESIS OF SUBSTITUTED ANTHRANILIC AMIDE COMPOUNDS, INTERMEDIATES AND SALTS THEREOF PI INDUSTRIES LTD. (IN) 2025-06-26 WO disclosed
WO-2025057193-A1 A METHOD FOR THE SYNTHESIS OF SUBSTITUTED ANTHRANILIC AMIDE COMPOUNDS, INTERMEDIATES AND SALTS THEREOF PI INDUSTRIES LTD. (IN) 2025-03-20 WO disclosed
CN-118619842-A Preparation method of 2-amino-5-bromo-N, 3-dimethylbenzamide 浙江予睿化学科技有限公司 2024-09-10 CN disclosed
CN-118619842-A Preparation method of 2-amino-5-bromo-N, 3-dimethylbenzamide 浙江予睿化学科技有限公司 2024-09-10 CN disclosed
CN-118619842-A Preparation method of 2-amino-5-bromo-N, 3-dimethylbenzamide 浙江予睿化学科技有限公司 2024-09-10 CN disclosed
WO-2024116197-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF INTERMEDIATE OF CYANTRANILIPROLE NATCO PHARMA LIMITED (IN) 2024-06-06 WO disclosed
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
WO-2009085816-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-09 WO disclosed
WO-2009061991-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-14 WO disclosed
US-7528260-B2 Method for preparing N-phenylpyrazole-1-carboxamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-05 US disclosed
WO-2009006061-A2 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-01-08 WO disclosed
EP-1828164-B1 METHOD FOR PREPARING N-PHENYLPYRAZOLE-1-CARBOXAMIDES DU PONT (US) 2008-09-17 EP disclosed
WO-2008082502-A2 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-10 WO disclosed
WO-2008070158-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-12 WO disclosed
US-20070299265-A1 Method for Preparing N-Phenylpyrazole-1-Carboxamides FMC CORPORATION 2007-12-27 US disclosed
EP-1828164-A1 METHOD FOR PREPARING N-PHENYLPYRAZOLE-1-CARBOXAMIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-09-05 EP disclosed
WO-2006062978-A1 METHOD FOR PREPARING N-PHENYLPYRAZOLE-1-CARBOXAMIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368602-A1 PROCESS FOR PREPARING CYANO SUBSTITUTED ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF QDPR, IDH3B, CYB5R3 KDM4E 883/4885CREBBP 4146/4885PKM 1650/4885
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ACMSD, ADCY10 KDM4E 1607/4885CREBBP 3054/4885PKM 1760/4885
US-20070299265-A1 Method for Preparing N-Phenylpyrazole-1-Carboxamides CPS1, KCNJ11, SCN3A KDM4E 3320/4885CREBBP 1320/4885PKM 1226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.