N-(Ethoxycarbonyl)Piperazine

N-(Ethoxycarbonyl)Piperazine

SCHEMBL3664173

CC(C)c1cc(C(C)C)c(S(=O)(=O)NC(=N)NN[C@@H](Cc2ccccc2)C(=O)O)c(C(C)C)c1.CCOC(=O)N1CCNCC1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PLAU P00749 18/20 0.54
▸ PLG P00747 14/20 0.54
▸ F10 P00742 7/20 0.54
▸ ST14 Q9Y5Y6 7/20 0.54
▸ F2 P00734 6/20 0.54
▸ PLAT P00750 4/20 0.54
▸ HPN P05981 3/20 0.54
▸ KLKB1 P03952 1/20 0.54
▸ TPSG1 Q9NRR2 1/20 0.54
▸ HGFAC Q04756 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-(Ethoxycarbonyl)Piperazine SCHEMBL2874625 0.81 PLAU (0.80) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL4606324 0.80 PLAU (0.80) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL1809303 0.80 PLAU (0.67) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2880394 0.79 PLAU (0.63) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2875164 0.79 PLAU (0.65) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL3660147 0.78 PLAU (0.58) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2875579 0.78 PLAU (0.61) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL3257068 0.78 PLAU (0.52) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL3664982 0.77 PLAU (0.49) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL3258134 0.77 PLAU (0.51) PLAUPLGF10ST14F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7659396-B2 Method for the production of phenylalanine derivatives WILEX AG (DE) 2010-02-09 — — US claimed
US-20090005562-A1 Method for the Production of Phenylalanine Derivatives WILEX AG (DE) 2009-01-01 — — US claimed
US-20050245757-A1 Method for the production of phenylalanine derivatives WILEX AG (DE) 2005-11-03 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005562-A1 Method for the Production of Phenylalanine Derivatives PAH, NPEPPS, DNPEP PLAU 1008/4885PLG 1705/4885F10 4029/4885
US-20050245757-A1 Method for the production of phenylalanine derivatives PAH, NPEPPS, DNPEP PLAU 1008/4885PLG 1705/4885F10 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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