N-(Ethoxycarbonyl)Piperazine

N-(Ethoxycarbonyl)Piperazine

SCHEMBL3660147

CC(C)c1cc(C(C)C)c(S(=O)(=O)NC(Cc2ccccc2C(=N)N)C(=O)O)c(C(C)C)c1.CCOC(=O)N1CCNCC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLAU P00749 17/20 0.58
PLG P00747 13/20 0.58
F10 P00742 9/20 0.58
ST14 Q9Y5Y6 8/20 0.58
F2 P00734 7/20 0.58
PLAT P00750 4/20 0.58
HPN P05981 4/20 0.58
KLKB1 P03952 1/20 0.58
TPSG1 Q9NRR2 1/20 0.58
HGFAC Q04756 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-(Ethoxycarbonyl)Piperazine SCHEMBL3257068 0.92 PLAU (0.52) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL3258134 0.91 PLAU (0.51) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2874625 0.86 PLAU (0.80) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL4606324 0.85 PLAU (0.80) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL1809303 0.81 PLAU (0.67) PLAUPLGF10ST14F2
SCHEMBL6129266 0.81 PLAU (0.61) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2880394 0.80 PLAU (0.63) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2875164 0.80 PLAU (0.65) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2875579 0.79 PLAU (0.61) PLAUPLGF10ST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL3664173 0.78 PLAU (0.54) PLAUPLGF10ST14F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7659396-B2 Method for the production of phenylalanine derivatives WILEX AG (DE) 2010-02-09 US claimed
US-20090005562-A1 Method for the Production of Phenylalanine Derivatives WILEX AG (DE) 2009-01-01 US claimed
US-7247724-B2 Method for the production of phenylalanine derivatives WILEX AG (DE) 2007-07-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005562-A1 Method for the Production of Phenylalanine Derivatives PAH, NPEPPS, DNPEP PLAU 1008/4885PLG 1705/4885F10 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.