Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664358 | 0.94 | AKR1C3 (0.45) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL10483666 | 0.88 | TSHR (0.56) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL29367715 | 0.86 | FOLH1 (0.50) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL23708 | 0.86 | FOLH1 (0.50) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL31090800 | 0.86 | FOLH1 (0.50) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL5553275 | 0.84 | FOLH1 (0.49) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL8837284 | 0.80 | HSPA5 (0.55) | TSHRFOLH1AKR1C3ALDH1A1ALOX15 | |
| SCHEMBL200212 | 0.80 | TSHR (0.59) | TSHRFOLH1AKR1C3ALDH1A1ALOX15 | |
| SCHEMBL7201768 | 0.79 | HTT (0.53) | TSHRCYP2C9HIF1AFOLH1AKR1C3 | |
| SCHEMBL617135 | 0.79 | ALDH1A1 (0.48) | TSHRAKR1C3ALDH1A1ALOX15HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8449200-B2 | Resin composition for sliding member and rolling bearing | NTN CORPORATION (JP) | 2013-05-28 | — | — | US | disclosed |
| US-8182155-B2 | Lubricating grease and lubricating grease-enclosed roller bearing | NTN CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20100142872-A1 | RESIN COMPOSITION FOR SLIDING MEMBER AND ROLLING BEARING | NTN CORPORATION (JP) | 2010-06-10 | — | — | US | disclosed |
| EP-2157135-A1 | RESIN COMPOSITION FOR SLIDE MEMBER AND ROLLER BEARING | NTN Corporation (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-20090232432-A1 | Lubricating grease and lubricating grease-enclosed roller bearing | NTN CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1956072-A1 | LUBRICATING GREASE AND LUBRICATING-GREASE-FILLED ROLLER BEARING | NTN CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |