Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665166 | 0.89 | TACR1 (0.47) | TACR1LIPEABHD6BACE1PTGDR2 | |
| SCHEMBL3669189 | 0.86 | TACR1 (0.44) | TACR1LIPEBACE1PTGDR2GPBAR1 | |
| SCHEMBL3669059 | 0.83 | TACR1 (0.43) | TACR1PTGDR2GPBAR1MEN1KMT2A | |
| SCHEMBL3672557 | 0.83 | TACR1 (0.55) | TACR1GPBAR1MEN1KMT2A | |
| SCHEMBL3674358 | 0.80 | MTOR (0.56) | TACR1 | |
| SCHEMBL3666876 | 0.77 | ABHD6 (0.54) | TACR1LIPEABHD6PTGDR2KDM4E | |
| SCHEMBL3671391 | 0.77 | TACR1 (0.43) | TACR1PTGDR2GPBAR1 | |
| SCHEMBL3668574 | 0.76 | GPBAR1 (0.52) | TACR1GPBAR1 | |
| SCHEMBL3666874 | 0.74 | ABHD6 (0.54) | TACR1LIPEABHD6PTGDR2KDM4E | |
| SCHEMBL3672254 | 0.73 | PTGDR2 (0.42) | TACR1BACE1PTGDR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |