Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.54 |
| ▸ | LIPE | Q05469 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666876 | 0.90 | ABHD6 (0.54) | ABHD6LIPEKDM4EALDH1A1TACR1 | |
| SCHEMBL1950749 | 0.85 | PTGDR2 (0.62) | ABHD6LIPEPTGDR2 | |
| SCHEMBL3671898 | 0.85 | LIPE (0.46) | ABHD6LIPEKDM4EALDH1A1TACR1 | |
| SCHEMBL3671609 | 0.84 | MLYCD (0.52) | TACR1MEN1KMT2AMTORAOC3 | |
| SCHEMBL3667568 | 0.82 | MGLL (0.42) | ABHD6LIPEKDM4EALDH1A1TACR1 | |
| SCHEMBL3668636 | 0.82 | MTOR (0.64) | TACR1MEN1KMT2AMGLLMTOR | |
| SCHEMBL3666865 | 0.78 | HDAC6 (0.56) | TACR1MEN1KMT2APTGDR2 | |
| SCHEMBL12542896 | 0.77 | PTGDR2 (0.52) | ABHD6LIPEMGLLPTGDR2PPARG | |
| SCHEMBL3665166 | 0.77 | TACR1 (0.47) | ABHD6LIPETACR1MEN1KMT2A | |
| SCHEMBL3672476 | 0.76 | MTOR (0.43) | ALDH1A1TACR1MTORAOC3PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |