Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | TACR1 | P25103 | 10/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674357 | 0.89 | MTOR (0.56) | MTORTACR1TP53MAPT | |
| SCHEMBL3671391 | 0.83 | TACR1 (0.43) | MTORTACR1 | |
| SCHEMBL3672557 | 0.83 | TACR1 (0.55) | TACR1 | |
| SCHEMBL3665168 | 0.80 | TACR1 (0.47) | TACR1 | |
| SCHEMBL3668638 | 0.77 | MTOR (0.64) | MTORTACR1TP53MAPT | |
| SCHEMBL3669059 | 0.77 | TACR1 (0.43) | TACR1 | |
| SCHEMBL3668574 | 0.76 | GPBAR1 (0.52) | TACR1 | |
| SCHEMBL3669189 | 0.75 | TACR1 (0.44) | TACR1 | |
| SCHEMBL3668636 | 0.74 | MTOR (0.64) | MTORTACR1TP53MAPT | |
| SCHEMBL3671389 | 0.72 | TACR1 (0.43) | MTORTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |