Glyphosate

Glyphosate

SCHEMBL3665221

O=C(O)CNCP(=O)(O)O.[LiH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ FOLH1 Q04609 7/20 0.37
▸ NAALAD2 Q9Y3Q0 1/20 0.34
▸ ENO1 P06733 1/20 0.32
▸ LDHA P00338 1/20 0.32
▸ SRR Q9GZT4 1/20 0.32
▸ ALKBH5 Q6P6C2 1/20 0.32
▸ SUCNR1 Q9BXA5 1/20 0.32
▸ EGLN1 Q9GZT9 1/20 0.32
▸ CA2 P00918 1/20 0.31
▸ CA4 P22748 1/20 0.31
▸ GGH Q92820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyphosate SCHEMBL11567772 1.00 LMNA (0.42) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL8515704 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL30579950 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL30579951 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL16440 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL29694166 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL214438 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL1964442 0.97 LMNA (0.43) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL11255222 0.95 LMNA (0.42) LMNAMEN1HPGDTSHRBLM
Glyphosate SCHEMBL10884848 0.95 LMNA (0.42) LMNAMEN1HPGDTSHRBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100331185-A1 Herbicidal Compositions of Lithium Glyphosate and Adjuvants COGNIS IP MANAGEMENT GMBH (DE) 2010-12-30 — — US disclosed
US-20100331185-A1 Herbicidal Compositions of Lithium Glyphosate and Adjuvants COGNIS IP MANAGEMENT GMBH (DE) 2010-12-30 — — US disclosed
EP-2211622-A2 HERBICIDAL COMPOSITIONS OF LITHIUM GLYPHOSATE AND ADJUVANTS Cognis IP Management GmbH (DE) 2010-08-04 — — EP disclosed
EP-2211622-A2 HERBICIDAL COMPOSITIONS OF LITHIUM GLYPHOSATE AND ADJUVANTS Cognis IP Management GmbH (DE) 2010-08-04 — — EP disclosed
WO-2009068226-A3 HERBICIDAL COMPOSITIONS OF LITHIUM GLYPHOSATE AND ADJUVANTS COGNIS IP MAN GMBH (DE) 2009-08-06 — — WO disclosed
WO-2009068226-A2 HERBICIDAL COMPOSITIONS OF LITHIUM GLYPHOSATE AND ADJUVANTS COGNIS IP MANAGEMENT GMBH (DE) 2009-06-04 — — WO disclosed
WO-2009068226-A2 HERBICIDAL COMPOSITIONS OF LITHIUM GLYPHOSATE AND ADJUVANTS COGNIS IP MANAGEMENT GMBH (DE) 2009-06-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331185-A1 Herbicidal Compositions of Lithium Glyphosate and Adjuvants GRIK3, SLC6A5, GLRA3 LMNA 2633/4885MEN1 4413/4885HPGD 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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