Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789708 | 1.00 | HSD11B1 (0.37) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL1838920 | 0.87 | HSD11B1 (0.46) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL1834964 | 0.87 | BCHE (0.40) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL1834967 | 0.87 | OPRM1 (0.46) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL1835882 | 0.87 | OPRM1 (0.46) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL1832648 | 0.85 | OPRK1 (0.43) | BCHEACHEOPRM1CHRM1DRD2 | |
| SCHEMBL1832267 | 0.85 | OPRK1 (0.43) | BCHEACHEOPRM1CHRM1DRD2 | |
| SCHEMBL1832646 | 0.85 | BCHE (0.38) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL3397207 | 0.83 | OPRM1 (0.47) | HSD11B1BCHEACHEOPRM1CHRM1 | |
| SCHEMBL1833774 | 0.82 | OPRM1 (0.42) | HSD11B1BCHEACHEOPRM1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-A2 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | Commissariat a L'Energie Atomique (FR) | 2010-03-10 | — | — | EP | disclosed |
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146174-A2 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |