SCHEMBL3665571

SCHEMBL3665571

Fc1ccc(-c2ncccn2)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
KDM4E B2RXH2 3/20 0.34
MPI P34949 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FFAR1 O14842 2/20 0.33
NPY5R Q15761 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
PARP1 P09874 1/20 0.32
HSD17B14 Q9BPX1 1/20 0.32
BRD4 O60885 1/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN1 Q05586 1/20 0.32
CYP2A6 P11509 1/20 0.31
GRM5 P41594 1/20 0.31
CASP6 P55212 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6270187 0.82 CCNE2 (0.41) KDM4ECES2CES1GRIN2BGRIN1
Hydrochloric Acid SCHEMBL28757672 0.78 CTSL (0.33) CTSLCTSSCTSKCES2CES1
SCHEMBL1200067 0.78 CYP2A6 (0.33) NPY5RCES1BRD4CYP2A6MAPT
SCHEMBL11996643 0.78 NOS3 (0.34) KDM4EL3MBTL1NPY5RBRD4LMNA
SCHEMBL28004077 0.78 MPL (0.35) KDM4EMPIL3MBTL1CYP3A4CYP2D6
SCHEMBL29901541 0.77 KDM4E (0.50) CTSLCTSSCTSKKDM4EL3MBTL1
SCHEMBL1356335 0.77 KDM4E (0.50) CTSLCTSSCTSKKDM4EL3MBTL1
SCHEMBL27991593 0.77 GRIN2B (0.33) CTSLCTSSCTSKGRIN2BGRIN1
SCHEMBL9756960 0.77 CLK4 (0.36) KDM4EL3MBTL1SMN1; SMN2
SCHEMBL8365589 0.77 FFAR1 (0.36) CTSLCTSSCTSKL3MBTL1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707966-A Method for continuously preparing trifluoro-phenylpyrimidine 华东理工大学 2025-03-28 CN claimed
CN-117814219-A Preparation containing trifluoro-benzene pyrimidine and application thereof 江苏海文农业发展有限公司 2024-04-05 CN claimed
CN-117016554-A Insecticidal composition containing trifluoro-phenylpyrimidine and celastrus angulatus and application thereof 河北省农林科学院植物保护研究所 2023-11-10 CN claimed
CN-116916751-A Insect and acarina pest control 先正达农作物保护股份公司 2023-10-20 CN claimed
CN-115633687-A Composition for preventing and treating mites, insects and nematodes and application 沈阳中化农药化工研发有限公司 2023-01-24 CN claimed
CN-115379759-A Pest control method, pest control agent composition, and pest control agent set 日本曹达株式会社 2022-11-22 CN claimed
CN-113325120-B Method for detecting content of trifluoro-benzene pyrimidine by GC-MS 湖南农业大学 2022-04-19 CN claimed
CN-112931520-A Mesoporous silica-based trifluorobenzene pyrimidine-loaded nanoparticle 扬州市职业大学(扬州市广播电视大学) 2021-06-11 CN claimed
CN-112385495-A Green and efficient planting method for high-quality japonica rice in rice and shrimp co-cropping field 江苏省农业科学院宿迁农科所 2021-02-23 CN claimed
CN-112205257-A Simple planting method for japonica rice in rice and shrimp co-cropping field 江苏省农业科学院宿迁农科所 2021-01-12 CN claimed
WO-2020030093-A1 PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF 上海泰禾国际贸易有限公司 2020-02-13 WO claimed
CN-110754275-A Method for preventing and treating citrus tree diseases and insect pests by combining biochemistry and biochemistry 赣南师范大学 2020-02-07 CN claimed
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN disclosed
CN-120202204-A Novel substituted tetrahydrones benzooxazepine 巴斯夫欧洲公司 2025-06-24 CN disclosed
CN-120202194-A Substituted as fungicides tetrahydrobenzodiazepine 巴斯夫欧洲公司 2025-06-24 CN disclosed
CN-114845551-B Enzyme enhanced root uptake of agrochemically active compounds 巴斯夫欧洲公司 2025-04-29 CN disclosed
CN-104342119-A Organic electrophosphorescent materials, preparing method thereof and organic electroluminescence devices OCEANS KING LIGHTING SCIENCE 2015-02-11 CN disclosed
CN-104342115-A Organic electrophosphorescent material and preparation method thereof and organic light-emitting device OCEANS KING LIGHTING SCIENCE 2015-02-11 CN disclosed
EP-2237669-A2 CHEMICAL COMPOUNDS Syngenta Limited (GB) 2010-10-13 EP disclosed
WO-2009081112-A2 CHEMICAL COMPOUNDS SYNGENTA LIMITED (GB) 2009-07-02 WO disclosed