Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877997 | 0.82 | TDP1 (0.44) | CCNE2CCNE1CDK2KDM4ENPC1 | |
| SCHEMBL3665571 | 0.82 | CTSL (0.39) | KDM4ECES2CES1GRM5CASP6 | |
| SCHEMBL31517695 | 0.81 | NPC1 (0.46) | KDM4ENPC1ADRA1ANISCH | |
| SCHEMBL4400229 | 0.81 | NPC1 (0.46) | KDM4ENPC1ADRA1ANISCH | |
| SCHEMBL7465152 | 0.79 | CNR2 (0.40) | CCNE2CCNE1CDK2BCAT1CNR2 | |
| SCHEMBL13294923 | 0.79 | CCNE2 (0.38) | CCNE2CCNE1CDK2BCAT1CNR2 | |
| SCHEMBL8365557 | 0.79 | FFAR1 (0.39) | CCNE2CCNE1CDK2HSD11B1WDR5 | |
| SCHEMBL25348324 | 0.78 | KMO (0.47) | CNR2NPC1GRM5 | |
| SCHEMBL14886178 | 0.78 | HCRTR1 (0.38) | KDM4ENPC1GRM5HCRTR1HCRTR2 | |
| SCHEMBL3038641 | 0.77 | CES2 (0.46) | CCNE2CCNE1CDK2BCAT1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086194-B1 | MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-21 | — | — | EP | claimed |
| US-6551668-B1 | Monodomain liquid crystal layer with an unambiguously defined direction of the layer normal z of the smectite phase wherein the layer normal z and the preferential direction n of the nematic or cholesteric phase (N* phase) form an angle of >/= 5 | AVENTIS RESEARCH & TECHNOLOGIES (DE) | 2003-04-22 | — | — | US | claimed |
| CN-105461699-B | Substituted heterocyclic compound and its application method and purposes | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-107141260-B | A kind of difluorophenyl miazines solid-state green emission luminous organic material and preparation method thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2019-06-14 | — | — | CN | disclosed |
| CN-107141260-A | A kind of difluorophenyl miazines solid-state green emission luminous organic material and preparation method thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2017-09-08 | — | — | CN | disclosed |
| WO-2005103200-A1 | CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE | AZ ELECTRONIC MATERIALS (GERMANY) GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
| EP-1591512-A1 | Chiral smectic liquid crystal mixture | AZ Electronic Materials (Germany) GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6737125-B2 | SUCH AS 8,9-DIFLUORO-7-(4-PENTYLPHENYL)-2-PROPYL-2,3-DIHYDRO-1H -CYCLOPENTA(A)NAPHTHALENE; FOR USE IN AUTOMOBILE INTERIORS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-05-18 | — | — | US | disclosed |
| US-6670514-B2 | For use in liquid-crystal displays; having high absolute values of dielectric anisotropy combined with a favorable viscosity/ clearing point ratios | CLARIANT FINANCE (BVI) LIMITED (VG) | 2003-12-30 | — | — | US | disclosed |
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | CLARIANT INTERNATIONAL LTD. | 2003-06-12 | — | — | US | disclosed |
| EP-1086194-B1 | MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-1994029405-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1994-12-22 | — | — | WO | disclosed |
| US-5340497-A | Ferroelectric liquid crystal | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-08-23 | — | — | US | disclosed |
| WO-1993025631-A1 | LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1993-12-23 | — | — | WO | disclosed |
| US-5204476-A | For use in chiral tilted smectic liquid crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0513262-A1 | 3,6-DISUBSTITUTED 2-HALOPYRIDINES | MERCK PATENT GmbH (DE) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992009576-A1 | 3,6-DISUBSTITUTED 2-HALOPYRIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1992-06-11 | — | — | WO | disclosed |
| EP-0433826-A2 | Fluorophenylpyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-26 | — | — | EP | disclosed |
| EP-0428665-A1 | FLUOROPHENYL PYRIMIDINES. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015116-A1 | FLUOROPHENYL PYRIMIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | SCO2, CYP2F1, OGFOD1 | CCNE2 538/4885CCNE1 629/4885CDK2 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.