SCHEMBL3666434

SCHEMBL3666434

Nc1[nH]c(=S)[nH]c(=O)c1N=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.56
LIG3 P49916 1/20 0.56
LIG4 P49917 1/20 0.56
HSD17B10 Q99714 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CDK1 P06493 1/20 0.44
CDK4 P11802 1/20 0.44
CDK2 P24941 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
MAPT P10636 5/20 0.37
KDM4E B2RXH2 3/20 0.37
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
PKM P14618 1/20 0.37
BRPF1 P55201 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191740 0.77 G6PD (0.53) LIG1LIG3LIG4CDK1CDK4
SCHEMBL4561128 0.77 G6PD (0.53) LIG1LIG3LIG4CDK1CDK4
SCHEMBL30902574 0.74 RPS6KA3 (0.54) ALDH1A1HPGDMAPTGAAL3MBTL1
SCHEMBL7767430 0.64 CDK2 (0.47) CDK1CDK4CDK2ALDH1A1MAPT
SCHEMBL11737794 0.61 KDM4E (0.43) HSD17B10CYP2C19ALDH1A1HPGDKDM4E
SCHEMBL10780551 0.61 CDK1 (0.53) CYP1A2CDK1CDK4CDK2ALDH1A1
SCHEMBL14123168 0.60 NPSR1 (0.47) LIG1LIG3LIG4HSD17B10CYP1A2
SCHEMBL11736849 0.59 KDM4E (0.46) HSD17B10ALDH1A1HPGDMAPTKDM4E
SCHEMBL14099178 0.58 CDK1 (0.33) CDK1CDK4CDK2CASP6
SCHEMBL13833302 0.58 CDK1 (0.66) CYP1A2CDK1CDK4CDK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846525-B2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 2005-01-25 US claimed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US claimed
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
CN-120153320-A Colored curable resin composition, color filter, display device, and solid-state imaging element 住友化学株式会社 2025-06-13 CN disclosed
CN-111344359-B Blue curable resin composition, blue color filter, and display device including the blue color filter 住友化学株式会社 2024-10-22 CN disclosed
WO-2024190528-A1 COLORING CURABLE RESIN COMPOSITION, OPTICAL FILTER, AND SOLID-STATE IMAGING ELEMENT 住友化学株式会社 2024-09-19 WO disclosed
WO-2024190526-A1 COLORED CURABLE RESIN COMPOSITION, OPTICAL FILTER, AND SOLID-STATE IMAGING ELEMENT 住友化学株式会社 2024-09-19 WO disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
US-5476604-A Crosslinked binder of polyvinyl alcohol HEWLETT-PACKARD COMPANY (US) 1995-12-19 US disclosed
EP-0675411-A1 Photosensitive resin composition and photosensitive film using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-10-04 EP disclosed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP disclosed