Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439475 | 0.64 | CDK2 (0.61) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL12464663 | 0.64 | — | — | |
| SCHEMBL10780551 | 0.64 | CDK1 (0.53) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL28538636 | 0.64 | CDK1 (1.00) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL9148762 | 0.62 | ALDH1A1 (0.36) | CDK2CDK1CDK4MAPTKMT2A | |
| SCHEMBL4458080 | 0.61 | CDK2 (0.41) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL7766477 | 0.61 | CDK2 (0.45) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL14490772 | 0.61 | CDK2 (0.47) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL7767432 | 0.61 | CDK2 (0.45) | CDK2CDK1CDK4MAPTKDM4E | |
| SCHEMBL11121357 | 0.59 | CDK2 (0.55) | CDK2CDK1CDK4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | claimed |
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | disclosed |