Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053821 | 0.94 | MAPT (0.41) | NPSR1MAPTMEN1POLBKMT2A | |
| SCHEMBL7442635 | 0.74 | MEN1 (0.47) | NPSR1MAPTMEN1POLBKMT2A | |
| SCHEMBL9583315 | 0.73 | NPSR1 (0.37) | NPSR1MAPTMEN1POLBKMT2A | |
| SCHEMBL28186423 | 0.70 | NPSR1 (0.35) | NPSR1MAPTMEN1POLBKMT2A | |
| SCHEMBL18629017 | 0.69 | MEN1 (0.46) | NPSR1MAPTMEN1POLBKMT2A | |
| SCHEMBL9583882 | 0.67 | MAPT (0.44) | NPSR1MAPTMEN1POLBKMT2A | |
| SCHEMBL4225099 | 0.67 | MAPT (0.40) | NPSR1MAPTCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL691739 | 0.66 | — | — | |
| SCHEMBL1606853 | 0.66 | NPSR1 (0.50) | NPSR1MAPTMEN1KMT2ACYP4F2 | |
| SCHEMBL1709532 | 0.65 | CYP3A4 (0.45) | NPSR1MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238144-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB Pharma, S.A. (BE) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009092764-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB PHARMA, S.A. (BE) | 2009-07-30 | — | — | WO | disclosed |
| EP-2049548-A1 | FUSED OXAZOLES & THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012010-A1 | FUSED OXAZOLES & THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS | UCB PHARMA, S.A. (BE) | 2008-01-31 | — | — | WO | disclosed |