SCHEMBL366720

SCHEMBL366720

C=C(C)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.47
PLA2G2A P14555 1/20 0.39
CTH P32929 1/20 0.39
TGFBR1 P36897 1/20 0.37
ALDH1A1 P00352 6/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
LMNA P02545 2/20 0.36
PTGS2 P35354 1/20 0.36
FAAH O00519 5/20 0.36
MEN1 O00255 2/20 0.34
APEX1 P27695 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 2/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11139095 1.00 EGLN1 (0.47) EGLN1PLA2G2ACTHTGFBR1ALDH1A1
SCHEMBL65636 0.91 EGLN1 (0.54) EGLN1PLA2G2ACTHTGFBR1ALDH1A1
Ammonia Solution, Strong SCHEMBL18139583 0.89 EGLN1 (0.52) EGLN1PLA2G2ACTHTGFBR1ALDH1A1
Acetic Acid SCHEMBL28463102 0.87 EGLN1 (0.50) EGLN1PLA2G2ACTHTGFBR1ALDH1A1
SCHEMBL4893549 0.84 TGFBR1 (0.35) EGLN1PLA2G2ATGFBR1ALDH1A1KDM4E
SCHEMBL23641442 0.82 TDP1 (0.37) TGFBR1TDP1
SCHEMBL4365280 0.82 MEN1 (0.36) TGFBR1ALDH1A1TDP1MEN1KMT2A
SCHEMBL8379994 0.81 MCL1 (0.39) EGLN1TGFBR1ALDH1A1FAAHKMT2A
SCHEMBL10594427 0.79 EGLN1 (0.52) EGLN1PLA2G2ACTHTGFBR1ALDH1A1
SCHEMBL8376801 0.78 TGFBR1 (0.35) EGLN1TGFBR1ALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920892-A Magnetic heterocyclic amine molecularly imprinted composite material and preparation method and application thereof 中国烟草总公司郑州烟草研究院 2022-08-19 CN claimed
CN-110201178-B Polymer functionalized modified mesoporous carbon nanoparticles and preparation and application thereof 沈阳药科大学 2022-08-02 CN claimed
CN-114621393-A Copolymer of N- (2-hydroxy) propyl methacrylamide and N-methacryloyl glycyl glycine and application thereof 华侨大学 2022-06-14 CN claimed
CN-103145932-A Long-circulating anti-tumor targeting drug carrier and preparation method thereof CHINESE ACAD INST CHEMISTRY 2013-06-12 CN claimed
CN-102276755-B Photopolymerizable chitosan derivative as well as preparation method and application thereof UNIV BEIJING CHEMICAL 2013-04-24 CN claimed
CN-102276755-A Photopolymerizable chitosan derivative as well as preparation method and application thereof 2011-12-14 CN claimed
US-12350337-B2 Polymeric drug delivery conjugates and methods of making and using thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-07-08 US disclosed
EP-4045087-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF University of Utah Research Foundation (US) 2022-08-24 EP disclosed
CN-114920892-A Magnetic heterocyclic amine molecularly imprinted composite material and preparation method and application thereof 中国烟草总公司郑州烟草研究院 2022-08-19 CN disclosed
US-20220249682-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION 2022-08-11 US disclosed
CN-110201178-B Polymer functionalized modified mesoporous carbon nanoparticles and preparation and application thereof 沈阳药科大学 2022-08-02 CN disclosed
CN-114621393-A Copolymer of N- (2-hydroxy) propyl methacrylamide and N-methacryloyl glycyl glycine and application thereof 华侨大学 2022-06-14 CN disclosed
CN-114621393-A Copolymer of N- (2-hydroxy) propyl methacrylamide and N-methacryloyl glycyl glycine and application thereof 华侨大学 2022-06-14 CN disclosed
US-5369142-A Curable mixtures with acrylic acid or methacrylic acid derivatives of amino acids THE OHIO STATE UNIVERSITY (US) 1994-11-29 US disclosed
EP-0403638-A1 POLYMERISABLE COMPOSITION KODAK LIMITED (GB) 1990-12-27 EP disclosed
WO-1990007527-A1 POLYMERISABLE COMPOSITION KODAK LIMITED (GB) 1990-07-12 WO disclosed
US-4663409-A Alpha, beta-unsaturated carbonyl modified amino acid monomer and polymers for biomedical uses BAUSCH & LOMB INCORPORATED (US) 1987-05-05 US disclosed
US-4396706-A ADDITION INTERPOLYMER PARTICLES, MATTES FUJI PHOTO FILM CO., LTD. (JP) 1983-08-02 US disclosed
US-4192784-A N-(TRIS(HYDROXYMETHYL)METHYL)ACRYLAMIDE OR THE METHACRYLAMIDE COPOLYMERS, BIOLOGICAL IMMOBILIZATION MAR-PHA SOCIETE D'ETUDES ET D'EXPLOITATION DE MARQUES (FR) 1980-03-11 US disclosed
US-4097470-A AMINO ACID, ACRYLATE OR ACRYLAMIDE ADDITION POLYMER CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350337-B2 Polymeric drug delivery conjugates and methods of making and using thereof PDCD1LG2, CD274, PDCD1 EGLN1 802/4885PLA2G2A 2904/4885CTH 2730/4885
US-20220249682-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF PDCD1LG2, CD274, PDCD1 EGLN1 802/4885PLA2G2A 2904/4885CTH 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.