Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366720 | 0.84 | EGLN1 (0.47) | TGFBR1EGLN1KDM4EALDH1A1PLA2G2A | |
| SCHEMBL11139095 | 0.84 | EGLN1 (0.47) | TGFBR1EGLN1KDM4EALDH1A1PLA2G2A | |
| SCHEMBL23641442 | 0.78 | TDP1 (0.37) | TGFBR1 | |
| SCHEMBL4365280 | 0.78 | MEN1 (0.36) | TGFBR1KDM4EALDH1A1 | |
| SCHEMBL8379994 | 0.78 | MCL1 (0.39) | TGFBR1EGLN1ALDH1A1 | |
| SCHEMBL25968074 | 0.75 | TGFBR1 (0.35) | TGFBR1EGLN1KDM4EALDH1A1 | |
| SCHEMBL8376801 | 0.75 | TGFBR1 (0.35) | TGFBR1EGLN1KDM4EALDH1A1 | |
| SCHEMBL65636 | 0.74 | EGLN1 (0.54) | TGFBR1EGLN1KDM4EALDH1A1PLA2G2A | |
| SCHEMBL366331 | 0.74 | TGFBR1 (0.42) | TGFBR1EGLN1KDM4EALDH1A1PLA2G2A | |
| Acetic Acid SCHEMBL8397576 | 0.74 | TGFBR1 (0.47) | TGFBR1EGLN1KDM4EALDH1A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193377-A1 | Radiolabeled Nanohybrids Targeting Solid Tumor Neovasculature and Method of Using Same | UNIVERSITY OF MARYLAND, BALTIMORE | 2008-08-14 | — | — | US | disclosed |
| EP-1768706-A2 | RADIOLABELED NANOHYBRIDS TARGETING SOLID TUMOR NEOVASCULATURE AND METHOD OF USING SAME | University of Maryland, Baltimore (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006012355-A2 | RADIOLABELED NANOHYBRIDS TARGETING SOLID TUMOR NEOVASCULATURE AND METHOD OF USING SAME | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2006-02-02 | — | — | WO | disclosed |