SCHEMBL4365280

SCHEMBL4365280

C=C(C)C(=O)NCC(=O)NCC(=O)NN

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CTSD P07339 1/20 0.35
TGFBR1 P36897 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31
KDM5C P41229 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
CASP6 P55212 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17802048 0.96 CTSD (0.38) MEN1KMT2ACTSDTGFBR1ALDH1A1
Hydrochloric Acid SCHEMBL8430763 0.94 MEN1 (0.37) MEN1KMT2ACTSDTGFBR1ALDH1A1
SCHEMBL23641442 0.84 TDP1 (0.37) TGFBR1TDP1
SCHEMBL366720 0.82 EGLN1 (0.47) MEN1KMT2ATGFBR1ALDH1A1TDP1
SCHEMBL11139095 0.82 EGLN1 (0.47) MEN1KMT2ATGFBR1ALDH1A1TDP1
SCHEMBL8373315 0.80 MCL1 (0.42) MEN1KMT2ATGFBR1
SCHEMBL8379994 0.79 MCL1 (0.39) KMT2ATGFBR1ALDH1A1
SCHEMBL4893549 0.78 TGFBR1 (0.35) TGFBR1ALDH1A1KDM4E
SCHEMBL8376801 0.77 TGFBR1 (0.35) TGFBR1ALDH1A1TDP1KDM4E
SCHEMBL25968074 0.77 TGFBR1 (0.35) TGFBR1ALDH1A1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001905-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2026-01-01 US disclosed
US-20220008543-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-01-13 US disclosed
US-20210214389-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA, LLC 2021-07-15 US disclosed
US-20210214389-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA, LLC 2021-07-15 US disclosed
EP-3843749-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME Osteoanalgesia, LLC (US) 2021-07-07 EP disclosed
EP-3843749-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME Osteoanalgesia, LLC (US) 2021-07-07 EP disclosed
WO-2020047231-A9 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2020-04-02 WO disclosed
WO-2020047231-A9 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2020-04-02 WO disclosed
WO-2020047231-A9 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2020-04-02 WO disclosed
WO-2020047231-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2020-03-05 WO disclosed
US-10172962-B2 Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2019-01-08 US disclosed
US-10092662-B2 Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2018-10-09 US disclosed
US-20180207296-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2018-07-26 US disclosed
EP-3269394-A1 MACROMOLECULAR DELIVERY SYSTEMS FOR NON-INVASIVE IMAGING, EVALUATION AND TREATMENT OF ARTHRITIS AND OTHER INFLAMMATORY DISEASES University of Utah Research Foundation (US) 2018-01-17 EP disclosed
EP-1737428-B1 MACROMOLECULAR DELIVERY SYSTEMS FOR NON-INVASIVE IMAGING, EVALUATION AND TREATMENT OF ARTHRITIS AND OTHER INFLAMMATORY DISEASES UNIV UTAH RES FOUND (US) 2017-08-30 EP disclosed
CN-103936945-A Novel efficient anti-tumor targeting drug carrier and preparation method thereof CHINESE ACAD INST CHEMISTRY 2014-07-23 CN disclosed
US-20090311182-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-12-17 US disclosed
US-20080159959-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-07-03 US disclosed
EP-1737428-A1 MACROMOLECULAR DELIVERY SYSTEMS FOR NON-INVASIVE IMAGING, EVALUATION AND TREATMENT OF ARTHRITIS AND OTHER INFLAMMATORY DISEASES University of Utah Research Foundation (US) 2007-01-03 EP disclosed
WO-2005097073-A1 MACROMOLECULAR DELIVERY SYSTEMS FOR NON-INVASIVE IMAGING, EVALUATION AND TREATMENT OF ARTHRITIS AND OTHER INFLAMMATORY DISEASES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220008543-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM PLG, PYGL, PPIG MEN1 425/4885KMT2A 3466/4885CTSD 2463/4885
US-20090311182-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases MMP1, MSR1, CD68 MEN1 3452/4885KMT2A 4274/4885CTSD 2400/4885
US-20210214389-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME NR3C1, GCG, NR3C2 MEN1 482/4885KMT2A 2522/4885CTSD 4172/4885
US-20260001905-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME NR3C1, HLA-DRB1, NR3C2 MEN1 2314/4885KMT2A 3589/4885CTSD 3076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.