SCHEMBL366722

SCHEMBL366722

Cc1c(O)ccc(Cl)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CYP3A4 P08684 4/20 0.42
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 6/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
HSD17B10 Q99714 4/20 0.38
ALOX15 P16050 2/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDE10A Q9Y233 1/20 0.38
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10083916 0.79 ALDH1A1 (0.50) CA1CA2CYP3A4ALDH1A1GAA
SCHEMBL4815999 0.79 ALDH1A1 (0.44) CYP3A4MAPK1ALDH1A1GAAMAPT
SCHEMBL335595 0.77 CYP3A4 (0.48) CA1CA2CYP3A4MAPK1ALDH1A1
SCHEMBL29566553 0.77 CYP3A4 (0.48) CA1CA2CYP3A4MAPK1ALDH1A1
SCHEMBL10703972 0.77 CA1 (0.48) CA1CA2CYP3A4MAPK1ALDH1A1
SCHEMBL3790032 0.75 CYP3A4 (0.46) CA1CA2CYP3A4MAPK1ALDH1A1
SCHEMBL4603633 0.75 ALOX15 (0.46) CYP3A4MAPK1ALDH1A1GAAMAPT
SCHEMBL911840 0.75 CYP3A4 (0.59) CA1CA2CYP3A4MAPK1ALDH1A1
SCHEMBL4856943 0.75 CYP3A4 (0.59) CA1CA2CYP3A4MAPK1ALDH1A1
SCHEMBL110840 0.75 CYP3A4 (0.59) CA1CA2CYP3A4MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2433617-B1 Cosmetic composition containing microcapsules HENKEL AG & CO KGAA (DE) 2019-05-15 EP claimed
EP-1900393-B1 Hydrogen peroxide activation with diones and imidazoles HENKEL AG & CO KGAA (DE) 2018-02-28 EP claimed
EP-1862198-B1 Brightening and/or dyeing agent with urea derivatives HENKEL AG & CO KGAA (DE) 2017-04-05 EP claimed
EP-2173314-B1 VAPORIZER SOLUTION, AND DYEING METHOD HENKEL AG & CO KGAA (DE) 2014-07-23 EP claimed
EP-1871486-B1 OXIDATION DYES COMPRISING PERSULFATES AND/OR PEROXODISULFATES HENKEL AG & CO KGAA (DE) 2014-07-09 EP claimed
EP-2012742-B1 BLEACHING AND/OR COLOURING AGENTS CONTAINING PIPERIDONES HENKEL AG & CO KGAA (DE) 2014-03-19 EP claimed
EP-2689773-A2 Protective hair dye with silicone block copolymers Henkel AG&Co. KGAA (DE) 2014-01-29 EP claimed
EP-2689803-A2 Protective hair dye with block copolymers Henkel AG&Co. KGAA (DE) 2014-01-29 EP claimed
EP-2689804-A2 Protective hair dye with silicone(s) and polymer(s) Henkel AG&Co. KGAA (DE) 2014-01-29 EP claimed
EP-2433617-A2 Cosmetic composition containing microcapsules Henkel AG & Co. KGaA (DE) 2012-03-28 EP claimed
WO-2007048473-A1 HAIR COLOURING AND/OR LIGHTENING METHOD WITH IMPROVED EFFICIENCY ACHIEVED BY UV LIGHT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-05-03 WO claimed
WO-2007025750-A1 AGENTS FOR THE TREATMENT OF KERATIN FIBRES CONTAINING NANOSCALE CALCIUM SALTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-08 WO claimed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO claimed
WO-2006111255-A1 PASTE-LIKE HAIR TREATMENT AGENT COMPRISING CYCLIC CARBOXYLATE ESTERS AND SILICATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-10-26 WO claimed
WO-2006108504-A1 OXIDATION DYES COMPRISING PERSULFATES AND/OR PEROXODISULFATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-10-19 WO claimed
EP-1030645-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2000-08-30 EP claimed
WO-1999066891-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 1999-12-29 WO claimed
EP-0039030-B1 COUPLER COMPONENTS FOR OXIDATIVE HAIR DYES, THEIR PREPARATION AND THEIR USE, AND HAIR DYEING COMPOSITIONS CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1984-07-18 EP claimed
EP-0039030-A1 Coupler components for oxidative hair dyes, their preparation and their use, and hair dyeing compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1981-11-04 EP claimed