Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63046 | 0.76 | LOXL2 (0.33) | PNMT | |
| SCHEMBL11436471 | 0.76 | ALDH1A1 (0.43) | TSHRCYP1A2HIF1AMEN1ALOX15 | |
| SCHEMBL21586425 | 0.76 | ALDH1A1 (0.37) | TSHRCYP3A4IDO1CYP2C9HIF1A | |
| SCHEMBL23201145 | 0.75 | CYP2C9 (0.39) | TSHRSCN4ACYP3A4GABRA1IDO1 | |
| SCHEMBL10039690 | 0.75 | SCN4A (0.37) | PNMTCYP2A6SCN4ACYP3A4 | |
| SCHEMBL3673507 | 0.74 | CYP2A6 (0.35) | CYP2A6IDO1CYP1A2HIF1AALOX15 | |
| SCHEMBL3676581 | 0.74 | MPO (0.35) | IDO1TAAR1 | |
| Hydrochloric Acid SCHEMBL30387703 | 0.73 | CYP2C9 (0.38) | TSHRSCN4ACYP3A4GABRA1IDO1 | |
| SCHEMBL1640771 | 0.73 | CYP3A4 (0.52) | PNMTCYP2A6CYP3A4IDO1HIF1A | |
| SCHEMBL1764819 | 0.72 | ALDH1A1 (0.52) | PNMTCYP2A6TSHRCYP3A4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |