Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203913 | 0.85 | MALT1 (0.59) | MALT1IDO1KDM4ACA12CA1 | |
| SCHEMBL11573216 | 0.83 | NR1H4 (0.45) | PTPN11NAMPTMEN1RAB9AKMT2A | |
| SCHEMBL10126784 | 0.83 | MEN1 (0.53) | MALT1IDO1CA12CA1BCHE | |
| SCHEMBL21224591 | 0.81 | TDP1 (0.58) | MALT1IDO1CA12CA1MEN1 | |
| SCHEMBL30479477 | 0.81 | MALT1 (0.46) | MALT1IDO1KDM4ACA12CA1 | |
| SCHEMBL19036151 | 0.79 | GAA (0.65) | IDO1KDM4ACTSKMEN1NPC1 | |
| SCHEMBL23736432 | 0.78 | MALT1 (0.43) | MALT1IDO1KDM4ACA12CA1 | |
| SCHEMBL25859374 | 0.78 | HDAC1 (0.50) | MALT1IDO1KDM4ACA12CA1 | |
| SCHEMBL9027360 | 0.78 | LMNA (0.48) | MALT1IDO1CA12CA1CA7 | |
| SCHEMBL6635582 | 0.78 | NPFFR1 (0.52) | CA1PTPN11NAMPTNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707984-A | Pyrazolotriazine and pyrazolopyrimidine derivative, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-03-28 | — | — | CN | disclosed |
| EP-2231667-A2 | BETA-LACTAMASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009091856-A2 | BETA-LACTAMASE INHIBITORS | MERCK & CO., INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| US-5298409-A | Of esters, antigen diastereomers which are stable analogs of the unstable ester transition states | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-29 | — | — | US | disclosed |
| US-5190865-A | Antibody-enhanced stereospecific hydrolyses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-03-02 | — | — | US | disclosed |