Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649697 | 0.89 | ALDH1A1 (0.40) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL4929584 | 0.86 | MIF (0.44) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL5864432 | 0.85 | ALDH1A1 (0.42) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL5664612 | 0.84 | ALDH1A1 (0.46) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL303932 | 0.80 | PKM (0.46) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL2246416 | 0.79 | ATM (0.56) | LMNAALDH1A1KMT2AMAPTCA12 | |
| Hydrochloric Acid SCHEMBL1169286 | 0.79 | PKM (0.45) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL3667447 | 0.78 | MALT1 (0.47) | KMT2ARAB9AMEN1CA12CA1 | |
| SCHEMBL6180339 | 0.78 | CA12 (0.52) | LMNAALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL22019039 | 0.77 | MAPT (0.37) | LMNAALDH1A1KMT2AMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |