SCHEMBL3667538

SCHEMBL3667538

CCOC(=O)NC(O)CCCO

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
ACHE P22303 7/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9601275 0.81 HRH3 (0.40) SMN1; SMN2MAPK1CYP4F2CYP4A11KMT2A
SCHEMBL8836776 0.80 GAA (0.46) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL9058964 0.80 SMN1; SMN2 (0.41) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL1348575 0.78 GAA (0.48) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL7804302 0.76 TDP1 (0.50) GAAKMT2A
SCHEMBL28054517 0.76 PTPN1 (0.38) KMT2AALDH1A1
SCHEMBL6984629 0.74 EPHX1 (0.47) SMN1; SMN2ACHEL3MBTL1ATMALDH1A1
SCHEMBL10453237 0.73
SCHEMBL26198819 0.73 SMN1; SMN2 (0.41) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL26198820 0.73 SMN1; SMN2 (0.41) MGAMGAASIMGAM2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-206591057-U The energy saver of diol mixture separation 天津市新天进科技开发有限公司 2017-10-27 CN disclosed
CN-206447795-U The energy saver of dihydric alcohol aqueous solution dehydration by-product monohydric alcohol 天津市新天进科技开发有限公司 2017-08-29 CN disclosed
CN-106748654-A Energy-saving process method and device that diol mixture is separate 天津市新天进科技开发有限公司 2017-05-31 CN disclosed
CN-106748653-A The energy-saving process method and device of dihydroxylic alcohols aqueous solution dehydration by-product monohydric alcohol 天津市新天进科技开发有限公司 2017-05-31 CN disclosed
US-8425542-B2 Aneurysm occlusion device containing bioactive and biocompatible copolymer shell and biocompatible metallic frame member WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-04-23 US disclosed
US-8425541-B2 Aneurysm occlusion device containing bioactive and biocompatible copolymer shell and a liquid embolic agent WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-04-23 US disclosed
US-8278406-B2 Bioactive and biocompatible polyurethane-buthanediol-glycosaminoglycan salt copolymers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-10-02 US disclosed
EP-2150259-A1 BIOACTIVE AND BIOCOMPATIBLE POLYURETHANE-BUTANEDIOL-GLYCOSAMINOGLYCAN SALT COPOLYMERS Wisconsin Alumni Research Foundation (US) 2010-02-10 EP disclosed
US-20090118761-A1 ANEURYSM OCCLUSION DEVICE CONTAINING BIOACTIVE AND BIOCOMPATIBLE COPOLYMER SHELL AND A LIQUID EMBOLIC AGENT WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-05-07 US disclosed
US-20090062834-A1 ANEURYSM OCCLUSION DEVICE CONTAINING BIOACTIVE AND BIOCOMPATIBLE COPOLYMER SHELL AND BIOCOMPATIBLE METALLIC FRAME MEMBER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-03-05 US disclosed
US-20080293906-A1 BIOACTIVE AND BIOCOMPATIBLE POLYURETHANE-BUTHANEDIOL-GLYCOSAMINOGLYCAN SALT COPOLYMERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-11-27 US disclosed
WO-2008134468-A1 BIOACTIVE AND BIOCOMPATIBLE POLYURETHANE-BUTANEDIOL-GLYCOSAMINOGLYCAN SALT COPOLYMERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-11-06 WO disclosed