Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27108524 | 0.83 | TAS1R3 (0.45) | SMN1; SMN2MAPK1ALOX15LMNAHTT | |
| SCHEMBL12928698 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1ALOX15LMNAHTT | |
| SCHEMBL9637270 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1ALOX15LMNAHTT | |
| SCHEMBL9810150 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1ALOX15LMNAHTT | |
| SCHEMBL3856821 | 0.81 | CA2 (0.36) | SMN1; SMN2MAPK1LMNAPOLBCA1 | |
| SCHEMBL9601275 | 0.80 | HRH3 (0.40) | SMN1; SMN2MAPK1LMNACYP4F2CYP4A11 | |
| SCHEMBL3667538 | 0.80 | MGAM (0.40) | SMN1; SMN2MAPK1LMNACYP4F2CYP4A11 | |
| SCHEMBL19337851 | 0.79 | TDP1 (0.47) | KMT2AGAACA1CA2 | |
| SCHEMBL26799152 | 0.79 | TDP1 (0.47) | KMT2AGAACA1CA2 | |
| SCHEMBL15502152 | 0.77 | GAA (0.42) | SMN1; SMN2MAPK1ALOX15LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996028157-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING L-ETRABAMINE, USES THEREOF, AND METHODS FOR PREPARING SAME | LABORATOIRES JACQUES LOGEAIS (FR) | 1996-09-19 | — | — | WO | claimed |