Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681331 | 0.99 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL3667774 | 0.87 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL22355416 | 0.86 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL9679431 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL11244958 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL10887268 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL10458798 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL10944580 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL11254582 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A | |
| SCHEMBL9680354 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPK1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |