Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666194 | 0.90 | MAPT (0.47) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL3668412 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL6517154 | 0.79 | L3MBTL1 (0.57) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL3660725 | 0.76 | ESR1 (0.52) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL3666080 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL13087217 | 0.71 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| Bicarbonate SCHEMBL28112150 | 0.69 | CES2 (0.61) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL21667786 | 0.69 | CA4 (0.62) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL15189750 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6223461 | 0.68 | ESR2 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240461-A1 | SUBSTITUTED FURANS AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009097991-A1 | SUBSTITUTED FURANS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-13 | — | — | WO | disclosed |