SCHEMBL578633

SCHEMBL578633

CCCCCCNS(=O)(=O)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.82
LMNA P02545 2/20 0.82
PKM P14618 2/20 0.82
KDM4E B2RXH2 1/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
TSHR P16473 1/20 0.71
EPHX2 P34913 1/20 0.68
TBXA2R P21731 1/20 0.66
MAPK1 P28482 2/20 0.63
RECQL P46063 1/20 0.62
CA12 O43570 1/20 0.59
CA9 Q16790 1/20 0.59
HTT P42858 1/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5020960 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL578832 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL578728 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL579136 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL1279062 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL633906 1.00 ALDH1A1 (0.82) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
SCHEMBL366844 0.98 ALDH1A1 (0.79) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
Bicarbonate SCHEMBL9492528 0.95 ALDH1A1 (0.74) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
Trimethylammonium SCHEMBL27862582 0.95 ALDH1A1 (0.74) ALDH1A1LMNAPKMKDM4ESMN1; SMN2
Bicarbonate SCHEMBL9491178 0.95 ALDH1A1 (0.74) ALDH1A1LMNAPKMKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105189508-B Naphthenic base nitrile Pyrazolopyridine ketone as JANUS kinase inhibitor 默沙东公司 2018-11-23 CN claimed
CN-105392816-A Heat resistant polyethylene terephthalate and a process for the preparation of the same ESTER IND LTD 2016-03-09 CN claimed
EP-2417198-A1 POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES Rhodia Opérations (FR) 2012-02-15 EP claimed
WO-2010115951-A1 POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES RHODIA OPERATIONS (FR) 2010-10-14 WO claimed
US-5922443-A Polymeric article, such as a medical catheter, and method for making the same BOSTON SCIENTIFIC GLENS FALLS CORP. 1999-07-13 US claimed
EP-0514913-B1 A polymeric article, such as a medical catheter, and method for making the same NAMIC CARIBE INC (PR) 1997-03-12 EP claimed
US-5484565-A Method for making a medical catheter NAMIC CARIBE, INC. (PR) 1996-01-16 US claimed
EP-0514913-A2 A polymeric article, such as a medical catheter, and method for making the same NAMIC CARIBE, INC. (PR) 1992-11-25 EP claimed
EP-0285946-B1 N-ALKYL-BENZENE SULFONAMIDES BAYER AG (DE) 1991-11-21 EP claimed
US-4891156-A STABILIZED PLASTICIZER BAYER AKTIENGESELLSCHAFT (DE) 1990-01-02 US claimed
CN-115003756-B Resin composition 松下知识产权经营株式会社 2024-10-01 CN disclosed
US-20230159569-A1 DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-05-25 US disclosed
CN-115003756-A Resin composition 松下知识产权经营株式会社 2022-09-02 CN disclosed
US-11174449-B2 Seal swell agents for lubricating compositions THE LUBRIZOL CORPORATION (US) 2021-11-16 US disclosed
US-11174449-B2 Seal swell agents for lubricating compositions THE LUBRIZOL CORPORATION (US) 2021-11-16 US disclosed
EP-0285946-B1 N-ALKYL-BENZENE SULFONAMIDES BAYER AG (DE) 1991-11-21 EP disclosed
US-4891156-A STABILIZED PLASTICIZER BAYER AKTIENGESELLSCHAFT (DE) 1990-01-02 US disclosed
EP-0285946-A2 N-alkyl-benzene sulfonamides BAYER AG (DE) 1988-10-12 EP disclosed
US-4053458-A INHIBITORS UOP INC. (US) 1977-10-11 US disclosed
US-4022828-A BIS-(SULFONAMIDO)-SULFIDES UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159569-A1 DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF HDAC6, PSMG3, PSMB2 ALDH1A1 2269/4885LMNA 2994/4885PKM 2820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.