Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668769 | 0.90 | HDAC1 (0.46) | HDAC1HDAC6LTB4R2HPGDGAA | |
| SCHEMBL3663868 | 0.83 | HDAC1 (0.45) | HDAC1HDAC6LTB4R2HPGDGAA | |
| SCHEMBL3663870 | 0.81 | HDAC1 (0.45) | HDAC1HDAC6LTB4R2HPGDGAA | |
| SCHEMBL1950223 | 0.77 | CTSL (0.49) | HDAC1HDAC6LTB4R2HPGDGAA | |
| SCHEMBL1947892 | 0.77 | FFAR1 (0.43) | HDAC1HDAC6LTB4R2GAAALDH1A1 | |
| SCHEMBL2036620 | 0.69 | HPGD (0.73) | HPGDGAAALDH1A1TRPV1CNR2 | |
| SCHEMBL3671754 | 0.66 | FSHR (0.47) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4630656 | 0.66 | PDCD1 (0.43) | LTB4R2KMT2A | |
| SCHEMBL1516136 | 0.66 | HPGD (0.71) | HPGDGAAALDH1A1TRPV1CNR2 | |
| SCHEMBL4585546 | 0.65 | TRPV1 (0.73) | HPGDGAAALDH1A1TRPV1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |