Sugi Predict

Sugi Predict / Compounds / SCHEMBL1947892

SCHEMBL1947892

SCHEMBL1947892

CCCCNC(=O)CN(Cc1cccc(-c2ccccc2OCC(=O)O)c1)C(=O)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 5/20 0.43
▸ KDM4E B2RXH2 2/20 0.42
▸ HTT P42858 2/20 0.41
▸ PLA2G1B P04054 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ ATG4B Q9Y4P1 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ LMNA P02545 1/20 0.41
▸ HDAC1 Q13547 2/20 0.41
▸ HDAC6 Q9UBN7 2/20 0.41
▸ LTB4R2 Q9NPC1 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ PTPN1 P18031 3/20 0.40
▸ PTGER1 P34995 1/20 0.40
▸ PTGER4 P35408 1/20 0.40
▸ PTGER3 P43115 1/20 0.40
▸ PTGER2 P43116 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1948540 0.88 FSHR (0.46) FFAR1KDM4EHTTPLA2G1BL3MBTL1
SCHEMBL3663868 0.85 HDAC1 (0.45) ALDH1A1HDAC1HDAC6LTB4R2GAA
SCHEMBL3663870 0.85 HDAC1 (0.45) ALDH1A1HDAC1HDAC6LTB4R2GAA
SCHEMBL1950346 0.81 PTGDR2 (0.47) FFAR1LTB4R2PTPN1
SCHEMBL1950223 0.78 CTSL (0.49) ALDH1A1HDAC1HDAC6LTB4R2GAA
SCHEMBL3668767 0.77 HDAC1 (0.46) HTTALDH1A1LMNAHDAC1HDAC6
SCHEMBL3668769 0.77 HDAC1 (0.46) HTTALDH1A1LMNAHDAC1HDAC6
SCHEMBL1946723 0.77 PTGDR2 (0.51) FFAR1LTB4R2PTPN1
SCHEMBL1948554 0.73 FSHR (0.48) KDM4EHTTALDH1A1LMNALTB4R2
SCHEMBL13769580 0.73 PTGDR2 (0.55) FFAR1HTTALDH1A1LMNAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US claimed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
WO-2009089192-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2009-07-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS HCAR2, PAH, PTGES2 FFAR1 202/4885KDM4E 3400/4885HTT 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.