Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342381 | 0.90 | KMT2A (0.68) | CNR1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL3681281 | 0.88 | MGLL (0.73) | CNR1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL4350770 | 0.83 | MEN1 (0.67) | MEN1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4358553 | 0.83 | MEN1 (0.71) | CNR1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL6567241 | 0.82 | EPHX1 (0.59) | MEN1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6567563 | 0.82 | CA12 (0.54) | MEN1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL20557568 | 0.81 | CNR1 (0.81) | CNR1GRIK1 | |
| SCHEMBL5359926 | 0.80 | SMN1; SMN2 (0.77) | CNR1MAPTKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6567652 | 0.79 | NPC1 (0.66) | CNR1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL5594862 | 0.79 | CXCR2 (0.62) | CNR1MEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234349-A1 | PHARMACEUTICAL COMBINATIONS OF A NICOTINE RECEPTOR MODULATOR AND A COGNITIVE ENHANCER | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | claimed |
| US-20070142450-A1 | Novel urea derivatives and their medical use | NEUROSEARCH A/S (DK) | 2007-06-21 | — | — | US | claimed |
| EP-2255848-A2 | Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer | NeuroSearch AS (DK) | 2010-12-01 | — | — | EP | disclosed |
| US-20070142450-A1 | Novel urea derivatives and their medical use | NEUROSEARCH A/S (DK) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234349-A1 | PHARMACEUTICAL COMBINATIONS OF A NICOTINE RECEPTOR MODULATOR AND A COGNITIVE ENHANCER | CHRNA10, CHRNA4, CHRNA5 | CNR1 99/4885MEN1 4874/4885MAPT 365/4885 |
| US-20070142450-A1 | Novel urea derivatives and their medical use | ACHE, NMUR1, NMUR2 | CNR1 32/4885MEN1 4363/4885MAPT 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.