Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074849 | 0.89 | PNMT (0.40) | PNMTTLR8GABRA1GABRB2KDM4E | |
| SCHEMBL3670219 | 0.88 | TLR8 (0.43) | PNMTTLR8GABRA1GABRB2TAAR1 | |
| SCHEMBL3670450 | 0.86 | TAAR1 (0.45) | GABRA1GABRB2TAAR1 | |
| SCHEMBL3674175 | 0.83 | GABRA1 (0.44) | PNMTTLR8GABRA1GABRB2DPP4 | |
| SCHEMBL10800343 | 0.78 | TLR8 (0.40) | PNMTTLR8 | |
| SCHEMBL1452942 | 0.77 | ALDH1A1 (0.41) | GABRA1GABRB2KDM4EALDH1A1GAA | |
| SCHEMBL29070930 | 0.76 | TLR8 (0.46) | TLR8 | |
| SCHEMBL25843243 | 0.76 | AR (0.35) | PNMTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL3934422 | 0.76 | PNMT (0.38) | PNMTGABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL10598924 | 0.75 | HTR2A (0.48) | TLR8KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |