Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030388 | 0.79 | ALDH1A1 (0.44) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL3669260 | 0.79 | ALDH1A1 (0.43) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL30534528 | 0.79 | ALDH1A1 (0.44) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL28718547 | 0.76 | POLB (0.48) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL5575751 | 0.76 | CYP1A2 (0.41) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL19063378 | 0.76 | ALDH1A1 (0.41) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL24703324 | 0.76 | CYP2A6 (0.40) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL13601826 | 0.76 | CYP1A2 (0.45) | POLBALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL3721788 | 0.74 | KDM4E (0.45) | POLBKDM4EMAOAMAPTRAD52 | |
| SCHEMBL29527767 | 0.73 | POLB (0.52) | POLBALDH1A1HSD17B10HIF1ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373822-B | Material containing benzopyrrole acridine structure and application thereof | 烟台九目化学股份有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-118373822-A | Material containing benzopyrrole acridine structure and application thereof | 烟台九目化学股份有限公司 | 2024-07-23 | — | — | CN | disclosed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | DDT, ACHE, GAP43 | POLB 3624/4885ALDH1A1 729/4885HSD17B10 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.