SCHEMBL3669302

SCHEMBL3669302

CCc1c(Cl)ccc(N)c1N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.35
TSHR P16473 6/20 0.34
TP53 P04637 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 1/20 0.33
GAA P10253 2/20 0.33
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR1A P08908 1/20 0.31
HTR1D P28221 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9361882 0.86 TAAR1 (0.34) CYP3A4TSHRTP53ALDH1A1GAA
SCHEMBL6162367 0.84 CYP3A4 (0.37) CYP3A4TSHRTP53ALDH1A1MAPK1
SCHEMBL3871396 0.82 ALDH1A1 (0.39) CYP3A4TSHRTP53ALDH1A1MAPK1
SCHEMBL7060663 0.80 NOS3 (0.37) CYP3A4TP53ALDH1A1MAPK1NOS3
SCHEMBL10341195 0.80 CYP3A4 (0.40) CYP3A4ALDH1A1GAANOS3NOS2
SCHEMBL3871164 0.80 TAAR1 (0.35) CYP3A4TSHRTP53ALDH1A1MAPK1
SCHEMBL398748 0.80 CTRC (0.36) GAANOS3NOS2TAAR1SMN1; SMN2
SCHEMBL30862051 0.80 CTRC (0.36) GAANOS3NOS2TAAR1SMN1; SMN2
SCHEMBL3685532 0.78 CA1 (0.39) CYP3A4TSHRALDH1A1MAPK1GAA
Ammonia Solution, Strong SCHEMBL10711080 0.75 TAAR1 (0.35) CYP3A4TSHRTP53NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed