Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.52 |
| ▸ | IDO1 | P14902 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654864 | 0.84 | PNMT (0.60) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL13692527 | 0.82 | SLC6A2 (0.66) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL8029239 | 0.82 | SLC6A2 (0.66) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL3058311 | 0.82 | PNMT (0.52) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL17045219 | 0.82 | PNMT (0.52) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL14044081 | 0.82 | IDO1 (0.52) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL268275 | 0.82 | SLC6A2 (0.66) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL17045232 | 0.82 | PNMT (0.52) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| Hydrochloric Acid SCHEMBL3279906 | 0.80 | SLC6A2 (0.63) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 | |
| Methane SCHEMBL20481902 | 0.80 | SLC6A2 (0.63) | PNMTSLC6A2SLC6A4SLC6A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-1230225-A2 | PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032632-A2 | PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |