SCHEMBL17045232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17045219	1.00	PNMT (0.52)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL3669308	0.82	PNMT (0.56)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL5654864	0.80	PNMT (0.60)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL3335731	0.80	IDO1 (0.48)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL268275	0.78	SLC6A2 (0.66)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL13692527	0.78	SLC6A2 (0.66)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL3058311	0.78	PNMT (0.52)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL14044081	0.78	IDO1 (0.52)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL6084229	0.78	SLC6A2 (0.50)	PNMTSLC6A2SLC6A4SLC6A3TAAR1
	SCHEMBL8029239	0.78	SLC6A2 (0.66)	PNMTSLC6A2SLC6A4SLC6A3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.