Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366953 | 0.91 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL365111 | 0.87 | EGFR (0.40) | EGFRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL364848 | 0.86 | GABRP (0.41) | EGFRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL366944 | 0.86 | ALDH1A1 (0.52) | EGFROXER1L3MBTL1TSHRTDP1 | |
| SCHEMBL366809 | 0.85 | EGFR (0.39) | EGFRL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL367044 | 0.83 | ELANE (0.39) | EGFRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL365589 | 0.83 | GABRP (0.42) | EGFRTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL364167 | 0.81 | GABRP (0.41) | EGFRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL365766 | 0.81 | STS (0.41) | EGFRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL367016 | 0.80 | TSHR (0.42) | EGFRL3MBTL1TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |