Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365111 | 0.88 | EGFR (0.40) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL364848 | 0.87 | GABRP (0.41) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL367043 | 0.87 | ALDH1A1 (0.50) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL366161 | 0.87 | ELANE (0.37) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL365589 | 0.84 | GABRP (0.42) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL366945 | 0.83 | EGFR (0.46) | ELANEALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL365766 | 0.83 | STS (0.41) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL364167 | 0.83 | GABRP (0.41) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL366953 | 0.80 | ALDH1A1 (0.46) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL366000 | 0.78 | ELANE (0.47) | ELANEGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |