SCHEMBL3669489

SCHEMBL3669489

CNCc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 8/20 0.45
NR1H4 Q96RI1 5/20 0.45
HDAC6 Q9UBN7 2/20 0.42
HDAC3 O15379 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
ESRRG P62508 1/20 0.41
CA2 P00918 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
MAP3K5 Q99683 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14964390 0.87 HDAC6 (0.47) EPHX2NR1H4HDAC6HDAC3HDAC8
SCHEMBL153898 0.84 KMT2A (0.56) EPHX2NR1H4HDAC6KMT2ACA2
SCHEMBL15197897 0.83 NR1H4 (0.46) NR1H4HDAC6HDAC8LOXL2KDM4E
SCHEMBL3671659 0.82 SMN1; SMN2 (0.43) EPHX2NR1H4HDAC6HDAC3HDAC8
Formaldehyde SCHEMBL29135914 0.81 KMT2A (0.52) EPHX2NR1H4HDAC6KMT2ACA2
SCHEMBL3687860 0.80 PLK1 (0.41) EPHX2NR1H4KMT2AESRRGCA2
SCHEMBL11298330 0.79 CA2 (0.46) CA2
SCHEMBL30912032 0.79 SRD5A2 (0.53) HDAC6MAPTKMT2A
SCHEMBL15120393 0.79 KMT2A (0.50) EPHX2NR1H4HDAC6KMT2ACA2
SCHEMBL3971183 0.79 ALDH1A1 (0.57) CYP3A4MAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160231658-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2016-08-11 US disclosed
US-8962226-B2 Organic photoreceptor, image forming apparatus, and process cartridge Konica Minolta, Inc. (JP) 2015-02-24 US disclosed
US-8889325-B2 Organic photoreceptor Konica Minolta, Inc. (JP) 2014-11-18 US disclosed
US-8404417-B2 Organic photoreceptor, image forming apparatus and process cartridge KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-03-26 US disclosed
US-8318396-B2 Organic photoreceptor and preparation method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-11-27 US disclosed
US-8298735-B2 Organic photoreceptor and manufacturing method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-10-30 US disclosed
US-20110217651-A1 IMAGE FORMATION METHOD AND IMAGE FORMATION APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-09-08 US disclosed
US-20110076603-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-03-31 US disclosed
US-20110045391-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-24 US disclosed
US-20110045393-A1 ORGANIC PHOTORECEPTOR AND MANUFACTURING METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-24 US disclosed
US-20110039197-A1 ORGANIC PHOTORECEPTOR AND PREPARATION METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-17 US disclosed
US-20110033204-A1 Organic Photoreceptor, Image Forming Apparatus and Process Cartridge Konica Minolta, Inc. (JP) 2011-02-10 US disclosed
US-7642296-B2 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-05 US disclosed
US-20070240609-A1 Photoinitiators IGM GROUP B.V. (NL) 2007-10-18 US disclosed
EP-1763499-B1 NEW PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2007-09-26 EP disclosed
EP-1763499-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-03-21 EP disclosed
WO-2005100292-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-27 WO disclosed