Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671963 | 0.84 | HRH4 (0.50) | SMN1; SMN2HDAC6HDAC8HDAC3CYP1A2 | |
| SCHEMBL3669489 | 0.82 | EPHX2 (0.45) | HDAC6EPHX2NR1H4HDAC8HDAC3 | |
| SCHEMBL3673599 | 0.82 | HRH4 (0.55) | SMN1; SMN2HDAC8HDAC3CYP1A2CYP2C19 | |
| SCHEMBL3673106 | 0.82 | HRH4 (0.55) | SMN1; SMN2HDAC8HDAC3CYP1A2CYP2C19 | |
| SCHEMBL3682984 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HDAC6EPHX2NR1H4 | |
| SCHEMBL1060928 | 0.80 | PLK1 (0.55) | ALDH1A1L3MBTL1KMT2APLK1 | |
| SCHEMBL3971183 | 0.80 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19PLK1 | |
| SCHEMBL2663103 | 0.78 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1HDAC6EPHX2NR1H4 | |
| SCHEMBL18602133 | 0.78 | KMT2A (0.57) | SMN1; SMN2ALDH1A1HDAC6EPHX2NR1H4 | |
| SCHEMBL153898 | 0.77 | KMT2A (0.56) | ALDH1A1HDAC6EPHX2NR1H4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |