SCHEMBL3669586

SCHEMBL3669586

COC(=O)CCNc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.51
HPGD P15428 4/20 0.51
POLB P06746 2/20 0.51
ALOX12 P18054 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
LMNA P02545 2/20 0.50
ALDH1A1 P00352 4/20 0.49
GAA P10253 3/20 0.47
HSP90AA1 P07900 1/20 0.47
CA12 O43570 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
PTPN7 P35236 1/20 0.46
PTPN12 Q05209 1/20 0.46
CASP3 P42574 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL505867 0.93 LMNA (0.55) MAPTPOLBHTTSMN1; SMN2LMNA
SCHEMBL14465499 0.91 LTA4H (0.48) MAPTHPGDPOLBALOX12MAPK1
SCHEMBL9756822 0.83 LMNA (0.60) MAPTPOLBSMN1; SMN2LMNAALDH1A1
SCHEMBL10491012 0.82 POLB (0.57) MAPTHPGDPOLBALOX12MAPK1
SCHEMBL31601639 0.81 SMN1; SMN2 (0.55) MAPTHPGDPOLBHTTSMN1; SMN2
SCHEMBL5184390 0.81 SMN1; SMN2 (0.55) MAPTHPGDPOLBMAPK1HTT
SCHEMBL13948407 0.81 MAPT (0.57) MAPTHPGDPOLBHTTSMN1; SMN2
SCHEMBL3666623 0.81 LMNA (0.41) MAPTHPGDPOLBALOX12MAPK1
SCHEMBL1472555 0.80 LMNA (0.66) MAPTSMN1; SMN2LMNAALDH1A1GAA
SCHEMBL2776004 0.80 TDP1 (0.51) MAPTHPGDPOLBALOX12MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625316-B1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE CO (US) 2023-08-23 EP disclosed
US-10815446-B2 Dispersants, method of making, and using same CHEVRON ORONITE COMPANY LLC (US) 2020-10-27 US disclosed
EP-3625316-A1 DISPERSANTS, METHOD OF MAKING, AND USING SAME Chevron Oronite Company LLC (US) 2020-03-25 EP disclosed
WO-2018211466-A1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE COMPANY LLC (US) 2018-11-22 WO disclosed
US-20180334635-A1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE COMPANY LLC 2018-11-22 US disclosed
EP-2235148-B1 ADDITIVE COMPOSITIONS WITH MICHAEL ADDUCTS OF N-SUBSTITUTED PHENYLENDIAMINES INFINEUM INT LTD (GB) 2014-09-17 EP disclosed
US-8530397-B2 Additive compositions INFINEUM INTERNATIONAL LIMITED (GB) 2013-09-10 US disclosed
EP-2235148-A1 ADDITIVE COMPOSITIONS WITH MICHAEL ADDUCTS OF N-SUBSTITUTED PHENYLENDIAMINES Infineum International Limited (GB) 2010-10-06 EP disclosed
EP-2075315-A1 Additive Compositions with Michael adducts of N-substituted phenylenediamines Infineum International Limited (GB) 2009-07-01 EP disclosed
US-20090156448-A1 Additive Compositions LANXESS SOLUTIONS US INC. 2009-06-18 US disclosed
WO-2009076082-A1 ADDITIVE COMPOSITIONS WITH MICHAEL ADDUCTS OF N-SUBSTITUTED PHENYLENDIAMINES INFINEUM INTERNATIONAL LIMITED (GB) 2009-06-18 WO disclosed