Sugi Predict

Sugi Predict / Compounds / SCHEMBL505867

SCHEMBL505867

SCHEMBL505867

COC(=O)CCNc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.55
▸ POLB P06746 2/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ CA12 O43570 3/20 0.51
▸ CA7 P43166 3/20 0.51
▸ CA14 Q9ULX7 3/20 0.51
▸ CA9 Q16790 2/20 0.51
▸ ALDH1A1 P00352 5/20 0.48
▸ MAPT P10636 4/20 0.48
▸ KDM4E B2RXH2 1/20 0.47
▸ LTA4H P09960 1/20 0.47
▸ KMT2A Q03164 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ AKT1 P31749 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ CA1 P00915 1/20 0.45
▸ TSHR P16473 1/20 0.44
▸ TOP2A P11388 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3669586 0.93 MAPT (0.51) LMNAPOLBSMN1; SMN2CA12CA7
SCHEMBL9756822 0.89 LMNA (0.60) LMNAPOLBSMN1; SMN2CA12CA7
SCHEMBL1472555 0.86 LMNA (0.66) LMNASMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL3508064 0.85 SMN1; SMN2 (0.51) LMNAPOLBSMN1; SMN2KDM4EKMT2A
SCHEMBL14465499 0.84 LTA4H (0.48) LMNAPOLBSMN1; SMN2CA12CA7
SCHEMBL537869 0.84 TOP2A (0.62) POLBSMN1; SMN2ALDH1A1LTA4HTOP2A
SCHEMBL13948407 0.83 MAPT (0.57) LMNAPOLBSMN1; SMN2ALDH1A1MAPT
SCHEMBL5184390 0.83 SMN1; SMN2 (0.55) LMNAPOLBSMN1; SMN2CA12CA7
SCHEMBL31601639 0.83 SMN1; SMN2 (0.55) LMNAPOLBSMN1; SMN2CA12CA7
SCHEMBL5151596 0.82 POLB (0.44) LMNAPOLBCA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111690695-A Enzymatic microfluidic online synthesis method of 3-phenylaminopropylhydroxamic acid 浙江工业大学 2020-09-22 — — CN claimed
CN-110437155-A Benzimidazole ketone compound and its purposes in antibechic, suppressing panting calming medicine WANG XINGLI 2019-11-12 — — CN claimed
WO-2011089183-A2 ANTICOAGULANT ANTIDOTES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-07-28 — — WO claimed
EP-1884513-A1 PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME Japan Tobacco, Inc. (JP) 2008-02-06 — — EP claimed
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents JAPAN TOBACCO INC. (JP) 2007-02-08 — — US claimed
EP-0966454-B1 DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA (DE) 2003-05-07 — — EP claimed
WO-2025064788-A2 CCR5 CONJUGATES AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-03-27 — — WO disclosed
US-20230295200-A1 STAT5 and STAT6 Inhibitors and Uses Thereof UNIV MICHIGAN (US) 2023-09-21 — — US disclosed
US-20230295200-A1 STAT5 and STAT6 Inhibitors and Uses Thereof UNIV MICHIGAN (US) 2023-09-21 — — US disclosed
US-20230295197-A1 STAT5 and STAT6 Degraders and Uses Thereof REGENTS OF THE UNIV OF MICHICAN (US) 2023-09-21 — — US disclosed
US-20230295197-A1 STAT5 and STAT6 Degraders and Uses Thereof REGENTS OF THE UNIV OF MICHICAN (US) 2023-09-21 — — US disclosed
EP-3625316-B1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE CO (US) 2023-08-23 — — EP disclosed
US-20230025301-A1 Novel Heterocyclic Derivatives with Cardiomyocyte Proliferation Activity for Treatment of Heart Diseases TONGJI UNIVERSITY (CN) 2023-01-26 — — US disclosed
US-4105655-A PHENYL-AZO-ANILINO DYESTUFF BAYER AKTIENGESELLSCHAFT (DE) 1978-08-08 — — US disclosed
US-4060544-A COUPLERS GAF CORPORATION (US) 1977-11-29 — — US disclosed
US-4048154-A POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-13 — — US disclosed
US-4039524-A Keto-amido containing phenylazo benzothiazole dyestuffs GAF CORPORATION (US) 1977-08-02 — — US disclosed
US-4036824-A Disazo dyestuffs containing A-O-alkylene-O-SO3 H group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 — — US disclosed
US-3962209-A PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 — — US disclosed
US-3931145-A POLYESTER GAF CORPORATION (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025301-A1 Novel Heterocyclic Derivatives with Cardiomyocyte Proliferation Activity for Treatment of Heart Diseases TNNI3, TNNT2, MKI67 LMNA 231/4885POLB 2280/4885SMN1; SMN2 948/4885
US-20230295197-A1 STAT5 and STAT6 Degraders and Uses Thereof STAT6, STAT5B, STAT5A LMNA 4687/4885POLB 3925/4885SMN1; SMN2 4125/4885
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents PYGL, GYS2, AGL LMNA 2123/4885POLB 3038/4885SMN1; SMN2 4705/4885
US-20230295200-A1 STAT5 and STAT6 Inhibitors and Uses Thereof STAT6, STAT5B, STAT5A LMNA 4716/4885POLB 4319/4885SMN1; SMN2 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.