SCHEMBL3669653

SCHEMBL3669653

CCc1c(Br)cc(N)c(N)c1CC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639148 0.85
SCHEMBL17692465 0.78 PTK2 (0.39) POLB
SCHEMBL238279 0.74 CYP3A4 (0.40) POLBMAPT
SCHEMBL103249 0.74 POLB (0.38) POLBMAPT
SCHEMBL29153429 0.74 LMNA (0.40) POLB
SCHEMBL15153043 0.73 GAA (0.50) POLBL3MBTL1GAAMAPT
SCHEMBL3678294 0.73 TAAR1 (0.32)
SCHEMBL3668733 0.73 GAA (0.42) GAA
SCHEMBL3672155 0.73 NOS3 (0.32) POLBL3MBTL1MAPT
SCHEMBL27593883 0.70 HTT (0.42) POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed